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Sunday, June 1, 2008

Risk Factors And Coronary Heart Disease

AHA Scientific Position

Extensive clinical and statistical studies have identified several factors
that increase the risk of coronary heart disease and heart attack. Major risk
factors are those that research has shown significantly increase the risk of
heart and blood vessel (cardiovascular) disease. Other factors are associated
with increased risk of cardiovascular disease, but their significance and
prevalence haven't yet been precisely determined. They're called contributing
risk factors.


The American Heart Association has identified several risk factors. Some of
them can be modified, treated or controlled, and some can't. The more risk
factors you have, the greater your chance of developing coronary heart disease.
Also, the greater the level of each risk factor, the greater the risk. For
example, a person with a total cholesterol of 300 mg/dL has a greater risk than
someone with a total cholesterol of 245 mg/dL, even though everyone with a total
cholesterol greater than 240 is considered high-risk.


What are the major risk factors that can't be changed?



  • Increasing age — Over 83 percent of people who die of coronary heart
    disease are 65 or older. At older ages, women who have heart attacks are more
    likely than men are to die from them within a few weeks.


  • Male sex (gender) — Men have a greater risk of heart attack than
    women do, and they have attacks earlier in life. Even after menopause, when
    women's death rate from heart disease increases, it's not as great as
    men's.


  • Heredity (including Race) — Children of parents with heart
    disease are more likely to develop it themselves. African Americans have more
    severe high blood pressure than Caucasians and a higher risk of heart disease.
    Heart disease risk is also higher among Mexican Americans, American Indians,
    native Hawaiians and some Asian Americans. This is partly due to higher rates of
    obesity and diabetes. Most people with a strong family history of heart disease
    have one or more other risk factors. Just as you can't control your age, sex and
    race, you can't control your family history. Therefore, it's even more important
    to treat and control any other risk factors you have.

What are the major risk factors you can modify, treat or control by
changing your lifestyle or taking medicine?



  • Tobacco smoke — Smokers' risk of developing coronary heart disease
    is 2–4 times that of nonsmokers. Cigarette smoking is a powerful independent
    risk factor for sudden cardiac death in patients with coronary heart disease;
    smokers have about twice the risk of nonsmokers. Cigarette smoking also acts
    with other risk factors to greatly increase the risk for coronary heart disease.
    People who smoke cigars or pipes seem to have a higher risk of death from
    coronary heart disease (and possibly stroke) but their risk isn't as great as
    cigarette smokers'. Exposure to other people's smoke increases the risk of heart
    disease even for nonsmokers.


  • High blood cholesterol — As blood cholesterol rises, so does risk of
    coronary heart disease. When other risk factors (such as high blood pressure and
    tobacco smoke) are present, this risk increases even more. A person's
    cholesterol level is also affected by age, sex, heredity and diet.


  • High blood pressure — High blood pressure increases the heart's
    workload, causing the heart to thicken and become stiffer. It also increases
    your risk of stroke, heart attack, kidney failure and congestive heart failure.
    When high blood pressure exists with obesity, smoking, high blood cholesterol
    levels or diabetes, the risk of heart attack or stroke increases several
    times.


  • Physical inactivity — An inactive lifestyle is a risk factor for
    coronary heart disease. Regular, moderate-to-vigorous physical activity helps
    prevent heart and blood vessel disease. The more vigorous the activity, the
    greater your benefits. However, even moderate-intensity activities help if done
    regularly and long term. Physical activity can help control blood cholesterol,
    diabetes and obesity, as well as help lower blood pressure in some
    people.


  • Obesity and overweight — People who have excess body fat — especially
    if a lot of it is at the waist — are more likely to develop heart disease and
    stroke even if they have no other risk factors. Excess weight increases the
    heart's work. It also raises blood pressure and blood cholesterol and
    triglyceride levels, and lowers HDL ("good") cholesterol levels. It can also
    make diabetes more likely to develop. Many obese and overweight people may have
    difficulty losing weight. But by losing even as few as 10 pounds, you can lower
    your heart disease risk.


  • Diabetes mellitus — Diabetes seriously increases your risk of
    developing cardiovascular disease. Even when glucose (blood sugar) levels are
    under control, diabetes increases the risk of heart disease and stroke, but the
    risks are even greater if blood sugar is not well controlled. About
    three-quarters of people with diabetes die of some form of heart or blood vessel
    disease. If you have diabetes, it's extremely important to work with your
    healthcare provider to manage it and control any other risk factors you can.
What other factors contribute to heart disease risk?

  • Individual response to stress may be a contributing factor.
    Some scientists have noted a relationship between coronary heart disease risk
    and stress in a person's life, their health behaviors and socioeconomic status.
    These factors may affect established risk factors. For example, people under
    stress may overeat, start smoking or smoke more than they otherwise would.


  • Drinking too much alcohol can raise blood pressure, cause
    heart failure and lead to stroke. It can contribute to high triglycerides,
    cancer and other diseases, and produce irregular heartbeats. It contributes to
    obesity, alcoholism, suicide and accidents.

    The risk of heart disease in
    people who drink moderate amounts of alcohol (an average of one
    drink for women or two drinks for men per day) is lower than in nondrinkers. One
    drink is defined as 1-1/2 fluid ounces (fl oz) of 80-proof spirits (such as
    bourbon, Scotch, vodka, gin, etc.), 1 fl oz of 100-proof spirits, 4 fl oz of
    wine or 12 fl oz of beer. It's not recommended that nondrinkers start
    using alcohol or that drinkers increase the amount they drink.

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